Undenatured Type II Collagen (UC-II®) For Joint Support: A Randomized, Double-blind, Placebo-controlled Study In Healthy Volunteers

Effect Decrease
Trial Design Double blind
Trial Length 1-6 months
Number of Subjects 46
Gender Both Genders
Age Range 45-64
Body Types Overweight
Notes for this study:
40mg of undenatured CII daily for four months appeared to be able to increase joint mobility in subjects who reported non-pathological joint pain (no arthritic conditions) and both prolonged how long one could exercise before joint pain occurred while improving recovery speeds after exercise.

Despite the benefits during exercise, there was no overall reduction in joint pain as assessed by KOOS (a subjective rating scale). Supplementation was not associated with any adverse effects.
Funding issues for this study:
Grant from InterHealth Nutraceuticals with one author as consultant