Vitamin B12
•Last Updated: September 28 2022
Cobalamin (Vitamin B12) is a water-soluble essential vitamin that is known to play roles in neurology.
Vitamin B12 is most often used for
Last Updated: September 28 2022
Note that Vitamin B12 is also known as:
- Cyanocobalamin
- cobalamin
- methylcobalamin
- 5-deoxyadenosylcobalamin
- adenosylcobalamin
- cobamamide
- dibencozide
- hydroxocobalamin
2.4 mcgs per day is the RDA for adults, generally (more is needed in some circumstances such as pregnancy). 100 mcg seems top be sufficient to reduce homocysteine for those with deficiency. Supplementation of vitamin B12 tends to be around 1,000 mcg (1 mg) of supplemental vitamin B12 to persons who are at risk for B12 insufficient or deficiency, mostly older individuals and vegans, though this dose is best only used for short periods with monitoring of levels so as to avoid excessive dosing and the potential risks.
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B vitamins are common ingredients of multivitamins, of course, but also of energy boosters, such as energy drinks. But while they are best known for their role in energy metabolism,[71] they may play a role in cancer biology through partaking in one-carbon metabolism[72] and thus in methylation reactions and DNA synthesis.
This hypothesis was substantiated in 2015 when a paper published by the New England Journal of Medicine caused a stir by reporting that nicotinamide (a form of vitamin B3 also known as niacinamide) could reduce the rate of new non-melanoma skin cancers...
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