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Interleukin 6

Interleukin 6 (IL-6) is a proinflammatory cytokine that is thought to reflect a more inflammatory state in the body.

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jul 5, 2013
Last Updated:

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Things To Know & Note

Also Known As

IL-6

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect interleukin 6
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Minor Very High See all 4 studies
A slight decrease in IL-6 concentrations has been noted, practical relevance unknown.
grade-c Minor - See study
A decrease in circulating IL-6 has been noted with fish oil supplementation
grade-c Minor - See study
A slight reduction in IL-6 has been reported in persons who are diagnosed with metabolic syndrome

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.

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