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Plasminogen Inhibitor 1

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:

Summary of Plasminogen Inhibitor 1

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on Plasminogen Inhibitor 1


Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect plasminogen inhibitor 1
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-c Fish Oil Minor - See study
An increase in PAI-1 is noted with fish oil supplementation
grade-c Trimethylglycine Minor - See study
An increase in PAI-1 concentrations has been noted with 4g of betaine supplementation daily over the course of six months in otherwise healthy adults.
grade-c Red Clover Extract - - See study
Circulating levels of PAI-1 (plasminogen activation inhibitor 1) have not been altered with supplementation of red clover isoflavones.
grade-d Perilla Oil  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.