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Symptoms of Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE or just Lupus) is an autoimmune disorder associated with outbreaks on skin tissue (and other immunological side-effects). Some supplements are thought to improve quality of life in persons with lupus.

Kamal
Research analysis lead by Kamal Patel
All content reviewed by Examine.com Team. Published:
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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect symptoms of systemic lupus erythematosus
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Fish Oil Notable Very High See all 7 studies
The decrease in symptoms of lupus as assessed by SLAM-R and BILAG at times reaches up to 50% symptom reduction and tends to exceed 30%, and the first pilot studies noted remission in all subjects (although they have not been replicated since). Oddly, benefit may come from lower doses (160mg EPA and 140mg DHA) with higher doses conferring less benefit
grade-c Vitamin D Minor - See study
Inflammatory symptoms associated with Lupus appear to be reduced with Vitamin D ingestion

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.