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Thyroid-Stimulating Hormone

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published: Jun 28, 2017
Last Updated:

Summary of Thyroid-Stimulating Hormone

Primary Information, Benefits, Effects, and Important Facts

Scientific Information on Thyroid-Stimulating Hormone

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Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect thyroid-stimulating hormone
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
Notes
grade-b Minor High See all 3 studies
An increase in Thyroid Stimulating Hormone (TSH) occurs both at the doses that suppress T3 and T4 and sometimes at lower doses where thyroid function is not impaired
grade-c - - See study
No significant influence of betaine on circulating TSH concentrations in serum.
grade-d Notable - See study
There was a notable reduction in one study where patients with subclinical hypothyroidism took 600 mg of a standardized extract (5% withanolides) for 8 weeks. More research is needed.

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.

grade-d