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VO2 Max

VO2 Max refers to the maximal oxygen consumption during exercise, and is thought to reflect the abilities of the cardiorespiratory system (heart and lungs) to handle high intensity cardiovascular exercise (anaerobic exercise).

Research analysis led by Kamal Patel.
All content reviewed by the Examine.com Team. Published:
Last Updated:

Human Effect Matrix

The Human Effect Matrix looks at human studies (it excludes animal and in vitro studies) to tell you what supplements affect vo2 max
Grade Level of Evidence
Robust research conducted with repeated double-blind clinical trials
Multiple studies where at least two are double-blind and placebo controlled
Single double-blind study or multiple cohort studies
Uncontrolled or observational studies only
Level of Evidence
? The amount of high quality evidence. The more evidence, the more we can trust the results.
Outcome Magnitude of effect
? The direction and size of the supplement's impact on each outcome. Some supplements can have an increasing effect, others have a decreasing effect, and others have no effect.
Consistency of research results
? Scientific research does not always agree. HIGH or VERY HIGH means that most of the scientific research agrees.
grade-b Creatine Minor Low See all 6 studies
Improvements in VO2 max are not wholly reliable, and appear to be low in magnitude.
grade-b Beta-Alanine - Moderate See all 5 studies
Effects on VO2 max are highly unreliable and not currently thought significant.
grade-b Colostrum - Very High See all 6 studies
All studies assessing the effects of colostrum in athletes subject to cardiovascular training have failed to find any difference between colostrum and whey protein (control) for influencing VO2 max.
grade-b Fish Oil  
grade-b Sodium Bicarbonate  
grade-c Ashwagandha  
grade-c Coenzyme Q10  
grade-c Echinacea  
grade-c Green Tea Catechins  
grade-c Resveratrol  
grade-c Caffeine  
grade-c Capsaicin  
grade-c Cordyceps  
grade-c Curcumin  
grade-c L-Carnitine  
grade-c Rhodiola Rosea  
grade-c Trimethylglycine  
grade-c Vitamin C  
grade-c Yerba mate  
grade-d Eleutherococcus senticosus  
grade-d HMB  
grade-d Marijuana  

All comparative evidence is now gathered in our ​A-to-Z Supplement Reference.

The evidence for each separate supplement is still freely available ​here.