How does vitamin B6 work to alleviate nausea?

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    Last Updated: October 13, 2024

    The mechanism for how vitamin B6 alleviates nausea is also largely unknown,[1] although it has been suspected since the 1940s that B6 functions as an antiemetic.[2][2] Currently, vitamin B6 is considered a viable treatment for nausea and vomiting in pregnancy, and it is sometimes combined[3] with the drug doxylamine.

    References

    1. ^Matok I, Clark S, Caritis S, Miodovnik M, Umans JG, Hankins G, Mattison DR, Koren GStudying the antiemetic effect of vitamin B6 for morning sickness: pyridoxine and pyridoxal are prodrugsJ Clin Pharmacol.(2014 Dec)
    2. ^ROSS JWThe vomiting of pregnancy and its managementJ Natl Med Assoc.(1948 Sep)
    3. ^Nuangchamnong N, Niebyl JDoxylamine succinate-pyridoxine hydrochloride (Diclegis) for the management of nausea and vomiting in pregnancy: an overviewInt J Womens Health.(2014 Apr 12)