Acute Kidney Injury

•Last Updated: November 20, 2025

Acute kidney injury occurs when kidney function suddenly deteriorates. This may result in the buildup of toxic waste products and fluids in the body. AKI can range from mild to severe. Kidney function can often be restored with proper medical treatment.

Last Updated:November 20, 2025

580 participants in trials and 1 meta-analysis

Examine Evidence Grades

BAcute Kidney Injury Incidence

D2 outcomes

Examine Database: Acute Kidney Injury

Intervention	Health Outcome	Grade	Evidence	Effect
Vitamin E	3 outcomes		6 Studies

Vitamin E

3 outcomes

Vitamin E

Research FeedRead all studies

Does a higher protein intake affect kidney adverse events in ICU patients?

In this meta-analysis of 14 randomized controlled trials in 7,280 adults who were admitted to the intensive care unit (ICU), a higher protein intake did not have a clear effect on adverse kidney outcomes or mortality risk.

Can silymarin protect against kidney damage?

Protective benefits of vitamin E for kidney injury

Examine Database References

Creatinine - Meng L, Liu S, Cui WRenal protective effects of vitamin E for drug-induced kidney injury: a meta-analysis.Front Pharmacol.(2025)