Amyotrophic Lateral Sclerosis

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    Last Updated: October 13, 2024

    Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that results in progressive muscle weakness. Since there is no cure, ALS results in complete paralysis.

    842 participants in 6 trials and 1 meta-analysis

    Examine Database: Amyotrophic Lateral Sclerosis

    Research FeedRead all studies

    Examine Database References

    1. Kidney Function - Groeneveld GJ, Veldink JH, van der Tweel I, Kalmijn S, Beijer C, de Visser M, Wokke JH, Franssen H, van den Berg LHA randomized sequential trial of creatine in amyotrophic lateral sclerosisAnn Neurol.(2003 Apr)
    2. Lung Function - Rosenfeld J, King RM, Jackson CE, Bedlack RS, Barohn RJ, Dick A, Phillips LH, Chapin J, Gelinas DF, Lou JSCreatine monohydrate in ALS: effects on strength, fatigue, respiratory status and ALSFRSAmyotroph Lateral Scler.(2008 Oct)
    3. Lung Function - Mazzini L, Balzarini C, Colombo R, Mora G, Pastore I, De Ambrogio R, Caligari MEffects of creatine supplementation on exercise performance and muscular strength in amyotrophic lateral sclerosis: preliminary resultsJ Neurol Sci.(2001 Oct 15)
    4. Lung Function - Drory VE, Gross DNo effect of creatine on respiratory distress in amyotrophic lateral sclerosisAmyotroph Lateral Scler Other Motor Neuron Disord.(2002 Mar)
    5. Amyotrophic Lateral Sclerosis Symptoms - Pastula DM, Moore DH, Bedlack RSCreatine for amyotrophic lateral sclerosis/motor neuron diseaseCochrane Database Syst Rev.(2012 Dec 12)
    6. Amyotrophic Lateral Sclerosis Symptoms - Shefner JM, Cudkowicz ME, Schoenfeld D, Conrad T, Taft J, Chilton M, Urbinelli L, Qureshi M, Zhang H, Pestronk A, Caress J, Donofrio P, Sorenson E, Bradley W, Lomen-Hoerth C, Pioro E, Rezania K, Ross M, Pascuzzi R, Heiman-Patterson T, Tandan R, Mitsumoto H, Rothstein J, Smith-Palmer T, MacDonald D, Burke D; NEALS ConsortiumA clinical trial of creatine in ALSNeurology.(2004 Nov 9)
    7. ALS Symptoms - Elia AE, Lalli S, Monsurrò MR, Sagnelli A, Taiello AC, Reggiori B, La Bella V, Tedeschi G, Albanese ATauroursodeoxycholic acid in the treatment of patients with amyotrophic lateral sclerosis.Eur J Neurol.(2016 Jan)