The international guidelines (KDIGO 2012[1]) now recommend protein intakes of about 0.8 grams per kilogram of bodyweight per day for CKD stages 3–5. However, these recommendations are similar to the recommended daily intake (RDA) values for the general population. Contrary to the international guidelines, the use of low protein diets as a dietary intervention in CKD management varies between countries and even within countries. In the U.S. and Canada, nutritional therapies are less often prescribed, probably due to the negative results of the Modification of Diet in Renal Disease (MDRD) study.[2] In contrast, low protein diets are more commonly prescribed in Europe.[3]
References
- ^Paul E Stevens, Adeera Levin, Kidney Disease: Improving Global Outcomes Chronic Kidney Disease Guideline Development Work Group MembersEvaluation and management of chronic kidney disease: synopsis of the kidney disease: improving global outcomes 2012 clinical practice guidelineAnn Intern Med.(2013 Jun 4)
- ^A S Levey, T Greene, G J Beck, A W Caggiula, J W Kusek, L G Hunsicker, S KlahrDietary protein restriction and the progression of chronic renal disease: what have all of the results of the MDRD study shown? Modification of Diet in Renal Disease Study groupJ Am Soc Nephrol.(1999 Nov)
- ^Vincenzo Bellizzi, Adamasco Cupisti, Francesco Locatelli, Piergiorgio Bolasco, Giuliano Brunori, Giovanni Cancarini, Stefania Caria, Luca De Nicola, Biagio R Di Iorio, Lucia Di Micco, Enrico Fiaccadori, Giacomo Garibotto, Marcora Mandreoli, Roberto Minutolo, Lamberto Oldrizzi, Giorgina B Piccoli, Giuseppe Quintaliani, Domenico Santoro, Serena Torraca, Battista F Viola, “Conservative Treatment of CKD” study group of the Italian Society of NephrologyLow-protein diets for chronic kidney disease patients: the Italian experienceBMC Nephrol.(2016 Jul 11)