Have any supplements been studied for chronic low back pain?

    Last Updated: October 25, 2023

    The following supplements have been studied for low back pain:

    • Vitamin D[1]
    • Amino acids[2]
    • Vitamin B12[3]
    • Alkaline minerals[4]
    • Collagen peptides, when tested alongside vitamin C and other supplements[5]

    Various herbal remedies have also been studied, including:[6]

    • Harpagophytum procumbens (devil’s claw)
    • Salix alba (white willow bark)
    • Symphytum officinale L. (comfrey root extract, studied for acute, non-specific low back pain)
    • Lavender essential oils (applied by acupressure)
    • Capsicum frutescens (cayenne)
    • Solidago chilensis

    References

    1. ^Ghai B, Bansal D, Kanukula R, Gudala K, Sachdeva N, Dhatt SS, Kumar VVitamin D Supplementation in Patients with Chronic Low Back Pain: An Open Label, Single Arm Clinical Trial.Pain Physician.(2017)
    2. ^Shell WE, Pavlik S, Roth B, Silver M, Breitstein ML, May L, Silver DReduction in Pain and Inflammation Associated With Chronic Low Back Pain With the Use of the Medical Food Theramine.Am J Ther.(2016)
    3. ^Mauro GL, Martorana U, Cataldo P, Brancato G, Letizia GVitamin B12 in low back pain: a randomised, double-blind, placebo-controlled study.Eur Rev Med Pharmacol Sci.(2000)
    4. ^Vormann J, Worlitschek M, Goedecke T, Silver BSupplementation with alkaline minerals reduces symptoms in patients with chronic low back pain.J Trace Elem Med Biol.(2001)
    5. ^Farì G, Santagati D, Pignatelli G, Scacco V, Renna D, Cascarano G, Vendola F, Bianchi FP, Fiore P, Ranieri M, Megna MCollagen Peptides, in Association with Vitamin C, Sodium Hyaluronate, Manganese and Copper, as Part of the Rehabilitation Project in the Treatment of Chronic Low Back Pain.Endocr Metab Immune Disord Drug Targets.(2022)
    6. ^Oltean H, Robbins C, van Tulder MW, Berman BM, Bombardier C, Gagnier JJHerbal medicine for low-back pain.Cochrane Database Syst Rev.(2014-Dec-23)