What developmental causes could contribute to infantile colic?

    Last Updated: October 25, 2023

    Intestinal hypermotility (increased contractions of the intestines), from a developmental dysregulation of the nervous system, may contribute to colic.[1][2][3] Imbalances of the parasympathetic and sympathetic nervous systems (which balance resting/digesting, and fight/flight responses, respectively) have been investigated but do not appear to be a cause of infantile colic.[4]

    References

    1. ^Gordon M, Biagioli E, Sorrenti M, Lingua C, Moja L, Banks SS, Ceratto S, Savino FDietary modifications for infantile colic.Cochrane Database Syst Rev.(2018-Oct-10)
    2. ^Biagioli E, Tarasco V, Lingua C, Moja L, Savino FPain-relieving agents for infantile colic.Cochrane Database Syst Rev.(2016-Sep-16)
    3. ^Camilleri M, Park SY, Scarpato E, Staiano AExploring hypotheses and rationale for causes of infantile colic.Neurogastroenterol Motil.(2017-Feb)
    4. ^Kirjavainen J, Jahnukainen T, Huhtala V, Lehtonen L, Kirjavainen T, Korvenranta H, Mikola H, Kero PThe balance of the autonomic nervous system is normal in colicky infants.Acta Paediatr.(2001-Mar)