How could diet affect cystic fibrosis?

    Last Updated: October 25, 2023

    If the small bowel has been affected by cystic fibrosis (or by common comorbidities such as celiac disease or Crohn's disease), a gluten-free diet, dietary counseling, and other dietary strategies may be helpful in treating associated digestive complications.[1][2]

    Oral calorie supplements are another common strategy used in cystic fibrosis to compensate for caloric and nutrient loss due to malabsorption. One review, however, has concluded that oral calorie supplements may be no more effective than dietary guidance or monitoring alone. In light of the current evidence, and considering the high costs of some oral calorie supplements, these may not be considered an essential cystic fibrosis therapy for all when less costly measures are just as effective and readily available.[3]

    Vitamin D is connected to lung function, and individuals with lower serum levels (<75 nmol/L) may see an increase in respiratory distress and dysfunction. The mechanism behind this is not yet fully understood, but further exploration of dietary/supplemental vitamin D in cystic fibrosis is warranted.[4]

    References

    1. ^Davies JC, Alton EW, Bush ACystic fibrosis.BMJ.(2007-Dec-15)
    2. ^Onady GM, Stolfi ADrug treatments for managing cystic fibrosis-related diabetes.Cochrane Database Syst Rev.(2020-Oct-19)
    3. ^Rosalind L Smyth, Oli RaynerOral calorie supplements for cystic fibrosisCochrane Database Syst Rev.(2017 May 4)
    4. ^Iniesta RR, Cook S, Oversby G, Koufaki P, Van der Linden ML, Vlachopoulos D, Williams CA, Urquhart DSSystematic review and meta-analysis: Associations of vitamin D with pulmonary function in children and young people with cystic fibrosis.Clin Nutr ESPEN.(2023-Apr)