What is the link between pancreatic function and lung function in cystic fibrosis?

The term ‘cystic fibrosis’ was coined because of the fibrocystic ulcerations that were found in the pancreases of early pediatric cases. Though lung functioning is now the most prominent hallmark of the condition, lung issues in early cases were often attributed to other issues (such as infections or asthma) then commonly seen in children. A strong link does exist between the degree of lung disease and the degree of pancreatic insufficiency seen in cystic fibrosis. Generally speaking, individuals with cystic fibrosis who have better lung function also seem to have a lesser degree of pancreatic issues. As a result of pancreatic insufficiency, cystic-fibrosis-related diabetes is a commonly-seen complication, occurring in up to 50% of adults with the condition.^[1]