What are some of the main medical treatments for depression?

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    Last Updated: October 13, 2024

    Today, antidepressants (chiefly SSRIs and SNRIs) are still the first-line treatment for depression, but their effects vary across individuals, so one may need to try different antidepressants to find the correct one.[1] Talk therapy is usually used in conjunction with antidepressants. If antidepressants fail to improve symptoms, brain stimulation therapies such as electroconvulsive therapy and transcranial magnetic stimulation can be effective tools for medication-resistant depression.[2]