What are the main signs and symptoms of depression?

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    Last Updated: October 13, 2024

    The symptoms of depression vary widely, such as sleeping too much or too little. This is one reason why diagnosing depression can be a challenge. Other symptoms include lost interest in favorite activities, feeling hopeless, and under-or overeating.[1] Symptoms may also vary by sex. For example, men with depression report higher rates of anger, aggression, substance use, and risk-taking compared to women.[2]