What causes dyslipidemia?

    Last Updated: October 25, 2023

    Dyslipidemia can have many causes, including diabetes, tobacco usage, liver and kidney disease, and hypothyroidism.[1]

    There are also different drugs that can cause dyslipidemia:

    • Thiazide diuretics
    • β-blockers
    • Cyclosporine
    • Glucocorticoids
    • Oral estrogens [2]

    Finally, there are genetic conditions that can cause dyslipidemia. For example, familial hypercholesterolemia causes high levels of cholesterol from an inability to metabolize LDL-C properly.[3]

    References

    1. ^Kopin L, Lowenstein CDyslipidemia.Ann Intern Med.(2017-Dec-05)
    2. ^Cicero AFG, Landolfo M, Ventura F, Borghi CCurrent pharmacotherapeutic options for primary dyslipidemia in adults.Expert Opin Pharmacother.(2019-Jul)
    3. ^Cuchel M, Bruckert E, Ginsberg HN, Raal FJ, Santos RD, Hegele RA, Kuivenhoven JA, Nordestgaard BG, Descamps OS, Steinhagen-Thiessen E, Tybjærg-Hansen A, Watts GF, Averna M, Boileau C, Borén J, Catapano AL, Defesche JC, Hovingh GK, Humphries SE, Kovanen PT, Masana L, Pajukanta P, Parhofer KG, Ray KK, Stalenhoef AF, Stroes E, Taskinen MR, Wiegman A, Wiklund O, Chapman MJ,Homozygous familial hypercholesterolaemia: new insights and guidance for clinicians to improve detection and clinical management. A position paper from the Consensus Panel on Familial Hypercholesterolaemia of the European Atherosclerosis Society.Eur Heart J.(2014-Aug-21)