So endometriosis is just uterine lining growing outside the uterus?

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    Last Updated: October 25, 2023

    Sort of, but endometriotic growths aren’t quite the same as the endometrial lining in the uterus. They’re not actually true endometrial tissue; they usually have differences that are visible under the microscope. Theories about development include “retrograde menstruation,” in which menses flow back up through the fallopian tubes and into the pelvic cavity; however, most women experience retrograde menstruation, and don’t experience endometriosis, and some people who have never menstruated have been diagnosed with endometriosis.[1][2][3] Other theories involve transformation of other cells into endometriotic cells.[4]

    References

    1. ^Bulletti C, Coccia ME, Battistoni S, Borini AEndometriosis and infertility.J Assist Reprod Genet.(2010-Aug)
    2. ^Li W, Lin A, Qi L, Lv X, Yan S, Xue J, Mu NImmunotherapy: A promising novel endometriosis therapy.Front Immunol.(2023)
    3. ^Who is Sampson, and what does he have to do with Endometriosis?
    4. ^Signorile PG, Viceconte R, Baldi ANew Insights in Pathogenesis of Endometriosis.Front Med (Lausanne).(2022)