How strong is the association between gestational diabetes and long-term health complications?

    Last Updated: October 13, 2024

    Gestational diabetes is associated with an increased risk of long-term complications in both the parent and the infant.[1][2][3] However, this association reflects shared environmental and genetic factors rather than a direct causal relationship to gestational diabetes, and some studies find no conclusive evidence of an association between gestational diabetes and adverse effects in offspring (such as the risk for childhood obesity[4] and metabolic diseases[5]). Moreover, even if gestational diabetes does increase the risk for certain conditions in offspring, it is unlikely that complex, multifactorial health conditions (like obesity) can be attributed to gestational diabetes alone.

    References

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    2. ^Dabelea D, Hanson RL, Lindsay RS, Pettitt DJ, Imperatore G, Gabir MM, Roumain J, Bennett PH, Knowler WCIntrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships.Diabetes.(2000-Dec)
    3. ^Ye W, Luo C, Huang J, Li C, Liu Z, Liu FGestational diabetes mellitus and adverse pregnancy outcomes: systematic review and meta-analysis.BMJ.(2022-May-25)
    4. ^Kim SY, England JL, Sharma JA, Njoroge TGestational diabetes mellitus and risk of childhood overweight and obesity in offspring: a systematic review.Exp Diabetes Res.(2011)
    5. ^Bianco ME, Josefson JLHyperglycemia During Pregnancy and Long-Term Offspring Outcomes.Curr Diab Rep.(2019-Nov-21)