Hemorrhoids

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    Last Updated: July 25, 2023

    Hemorrhoids are a common medical condition in which blood vessels in the anus become swollen and displaced. Hemorrhoids are not particularly harmful, but they can cause significant discomfort, including bleeding, itching, and pain.

    Hemorrhoids falls under the Gut Health category.

    What are hemorrhoids?

    Hemorrhoids are swollen blood vessels within the anal canal/rectum (internal hemorrhoids) or around the opening of the anus (external hemorrhoids). Hemorrhoids result from the pathological enlargement of anal cushions. Anal cushions are a part of anal anatomy that help maintain continence (the ability to control bowel movements) by filling with blood to seal the rectum, and draining during defecation. If this filling and draining process isn’t working properly, they can become enlarged and cause symptoms. Hemorrhoids are generally not harmful, apart from causing discomfort.[1]

    Hemorrhoids are a common condition, with a U.S. survey finding a prevalence of 4.4% in the general public. However, some research reports rates of up to 40%.[2][3] Hemorrhoids affect both sexes equally and prevalence peaks between ages 45 and 65.[2] It’s suggested that by age 50, roughly half of people will have experienced hemorrhoids at some point in their life.[4]

    What are the main signs and symptoms of hemorrhoids?

    Hemorrhoids commonly cause rectal bleeding, itching, and pain. Sometimes, mucousy discharge or fecal soiling may also occur.[1] If bleeding occurs, it is usually bright red, painless, and may be visible during or right after a bowel movement in the toilet bowl or on toilet paper.[5] A study that assessed the frequency of hemorrhoids in participants undergoing colorectal cancer screening found that over half of individuals with hemorrhoid disease did not have any symptoms.[3]

    Symptoms can also depend on the type of hemorrhoid. External hemorrhoids may be visible as a swollen bump on the anal opening and can be quite painful, as the area has many nerves for sensing pain. Alternatively, internal hemorrhoids are usually not visible unless they are prolapsed (the blood vessel becomes displaced and protrudes out of the anus) and are often painless, as there are no pain receptors in that region of the rectum. Both types of hemorrhoids can become thrombosed, during which a harmless (but painful) blood clot forms in the hemorrhoid.[1][4]

    Many of the symptoms of hemorrhoids can occur due to other more serious health conditions and therefore proper diagnosis by a healthcare provider is always recommended.[1]

    How are hemorrhoids diagnosed?

    A clinician usually diagnoses hemorrhoids with a physical exam, which may include an examination of the anus and rectum to check for visible hemorrhoids, or a digital rectal exam during which a finger is used to feel for any abnormalities in the rectum. Sometimes an endoscope may be required to diagnose internal hemorrhoids. The endoscope is a small tube with a light and camera that is inserted into the rectum to evaluate the inner tissues.[1][3]

    Internal hemorrhoids are often graded based on the degree of prolapse:[6]

    • Grade I: painless swelling of the hemorrhoid occurs.
    • Grade II: hemorrhoid protrudes from the anus during bowel movements and spontaneously returns to normal position.
    • Grade III: hemorrhoid protrudes from the anus during bowel movements and must be manually returned to position.
    • Grade IV: hemorrhoid protrudes from the anus during bowel movements and cannot be returned to position.

    What are some of the main medical treatments for hemorrhoids?

    The initial treatment of hemorrhoids usually involves lifestyle changes focused on reducing constipation, including consuming more fiber, increasing fluid intake, using stool softeners, avoiding straining on the toilet, and improving anal hygiene by cleansing with warm water and using unscented wipes in place of toilet paper.[7]

    Over-the-counter topical creams/ointments and suppositories containing a variety of ingredients (e.g., zinc, corticosteroids, anesthetics, phenylephrine) can improve symptoms temporarily, but there is little evidence to support their long-term efficacy and safety.[7][6] Prescription topical medications containing nitroglycerin or nifedipine can also be helpful for managing pain.[6]

    For more severe hemorrhoids, or when initial treatments have failed, a clinician may perform nonsurgical (e.g., rubber band ligation) or surgical interventions (e.g., hemorrhoidectomy) to remove the hemorrhoid. However, these more invasive treatments are associated with a high risk of hemorrhoid recurrence and post-procedure pain.[8][6]

    Have any supplements been studied for hemorrhoids?

    Fiber supplementation helps to soften stool and reduce constipation, which can minimize irritation to the anal cushions and improve healing. A meta-analysis of controlled trials found that fiber supplementation, most often psyllium, reduced the risk of overall hemorrhoid symptoms by half and was particularly effective for reducing the risk of bleeding. However, it can take up to 6 weeks for these benefits to take effect. Once hemorrhoids have healed, fiber supplementation can be continued as a preventative measure.[1]

    Bioflavonoid supplementation, particularly micronized purified flavonoid fraction (MPFF) containing 90% diosmin and 10% hesperidin, was assessed in two recent meta-analyses of controlled trials. One meta-analysis reported a reduction in bleeding, anal leakage, and overall symptoms, while the other only found an effect for reduced bleeding.[9][10] MPFF is thought to work by reducing vein inflammation and increasing vein tone (the tightness of the vein).[9] While these products are commonly used in other parts of the world, they are not currently approved by the U.S. Food and Drug Administration for hemorrhoid treatment.[6]

    How could diet affect hemorrhoids?

    A high-fiber diet (25 to 35 grams daily), including adequate fluid intake, is considered to be the best first-line intervention for the management and prevention of hemorrhoids.[11][6] Fiber is found in plant-based foods like vegetables, fruits, whole grains, legumes, nuts, and seeds. Sometimes, going from a low-fiber diet to a high-fiber diet can cause symptoms like bloating, gas, and abdominal discomfort, but slowly increasing fiber intake over time can help to minimize these symptoms. Observational research has suggested that higher consumption of spicy foods is associated with an increased risk of hemorrhoids, but this claim has not been supported by interventional trials.[12][13][7]

    Are there any other treatments for hemorrhoids?

    Sitz baths, which involve sitting in a warm tub of water for 10 to 15 minutes several times a day, are often recommended by healthcare providers for hemorrhoids, but a meta-analysis was unable to find any strong evidence for improvements in pain or healing time. Regardless, people using a sitz bath often reported finding it soothing, and there is no apparent harm from the practice.[14]

    Pelvic floor physiotherapy may play a role in improving long-term outcomes for recurrent hemorrhoids for people with dyssynergic defecation, which is a pelvic floor dysfunction that can make bowel movements difficult. However, most of the research in this field has been related to anal fissures rather than hemorrhoids.[8]

    What causes hemorrhoids?

    Although hemorrhoids are not fully understood, they are thought to occur when the connective tissues within the anal cushion weaken, allowing the blood vessels in the region to become enlarged and displaced.

    Generally, hemorrhoids are associated with conditions that increase pressure in the abdomen or create a shear force against the anal cushions, such as:[6][8][3][11]

    • Constipation (either from hard or lumpy stool or straining during bowel movements)
    • Pregnancy and vaginal delivery
    • Chronic diarrhea
    • Cirrhosis with ascites (fluid in the abdominal cavity)
    • Obesity
    • Anal intercourse
    • Pelvic floor dysfunction

    Examine Database: Hemorrhoids

    Frequently asked questions

    What are hemorrhoids?

    Hemorrhoids are swollen blood vessels within the anal canal/rectum (internal hemorrhoids) or around the opening of the anus (external hemorrhoids). Hemorrhoids result from the pathological enlargement of anal cushions. Anal cushions are a part of anal anatomy that help maintain continence (the ability to control bowel movements) by filling with blood to seal the rectum, and draining during defecation. If this filling and draining process isn’t working properly, they can become enlarged and cause symptoms. Hemorrhoids are generally not harmful, apart from causing discomfort.[1]

    Hemorrhoids are a common condition, with a U.S. survey finding a prevalence of 4.4% in the general public. However, some research reports rates of up to 40%.[2][3] Hemorrhoids affect both sexes equally and prevalence peaks between ages 45 and 65.[2] It’s suggested that by age 50, roughly half of people will have experienced hemorrhoids at some point in their life.[4]

    What are the main signs and symptoms of hemorrhoids?

    Hemorrhoids commonly cause rectal bleeding, itching, and pain. Sometimes, mucousy discharge or fecal soiling may also occur.[1] If bleeding occurs, it is usually bright red, painless, and may be visible during or right after a bowel movement in the toilet bowl or on toilet paper.[5] A study that assessed the frequency of hemorrhoids in participants undergoing colorectal cancer screening found that over half of individuals with hemorrhoid disease did not have any symptoms.[3]

    Symptoms can also depend on the type of hemorrhoid. External hemorrhoids may be visible as a swollen bump on the anal opening and can be quite painful, as the area has many nerves for sensing pain. Alternatively, internal hemorrhoids are usually not visible unless they are prolapsed (the blood vessel becomes displaced and protrudes out of the anus) and are often painless, as there are no pain receptors in that region of the rectum. Both types of hemorrhoids can become thrombosed, during which a harmless (but painful) blood clot forms in the hemorrhoid.[1][4]

    Many of the symptoms of hemorrhoids can occur due to other more serious health conditions and therefore proper diagnosis by a healthcare provider is always recommended.[1]

    How are hemorrhoids diagnosed?

    A clinician usually diagnoses hemorrhoids with a physical exam, which may include an examination of the anus and rectum to check for visible hemorrhoids, or a digital rectal exam during which a finger is used to feel for any abnormalities in the rectum. Sometimes an endoscope may be required to diagnose internal hemorrhoids. The endoscope is a small tube with a light and camera that is inserted into the rectum to evaluate the inner tissues.[1][3]

    Internal hemorrhoids are often graded based on the degree of prolapse:[6]

    • Grade I: painless swelling of the hemorrhoid occurs.
    • Grade II: hemorrhoid protrudes from the anus during bowel movements and spontaneously returns to normal position.
    • Grade III: hemorrhoid protrudes from the anus during bowel movements and must be manually returned to position.
    • Grade IV: hemorrhoid protrudes from the anus during bowel movements and cannot be returned to position.
    What are some of the main medical treatments for hemorrhoids?

    The initial treatment of hemorrhoids usually involves lifestyle changes focused on reducing constipation, including consuming more fiber, increasing fluid intake, using stool softeners, avoiding straining on the toilet, and improving anal hygiene by cleansing with warm water and using unscented wipes in place of toilet paper.[7]

    Over-the-counter topical creams/ointments and suppositories containing a variety of ingredients (e.g., zinc, corticosteroids, anesthetics, phenylephrine) can improve symptoms temporarily, but there is little evidence to support their long-term efficacy and safety.[7][6] Prescription topical medications containing nitroglycerin or nifedipine can also be helpful for managing pain.[6]

    For more severe hemorrhoids, or when initial treatments have failed, a clinician may perform nonsurgical (e.g., rubber band ligation) or surgical interventions (e.g., hemorrhoidectomy) to remove the hemorrhoid. However, these more invasive treatments are associated with a high risk of hemorrhoid recurrence and post-procedure pain.[8][6]

    Have any supplements been studied for hemorrhoids?

    Fiber supplementation helps to soften stool and reduce constipation, which can minimize irritation to the anal cushions and improve healing. A meta-analysis of controlled trials found that fiber supplementation, most often psyllium, reduced the risk of overall hemorrhoid symptoms by half and was particularly effective for reducing the risk of bleeding. However, it can take up to 6 weeks for these benefits to take effect. Once hemorrhoids have healed, fiber supplementation can be continued as a preventative measure.[1]

    Bioflavonoid supplementation, particularly micronized purified flavonoid fraction (MPFF) containing 90% diosmin and 10% hesperidin, was assessed in two recent meta-analyses of controlled trials. One meta-analysis reported a reduction in bleeding, anal leakage, and overall symptoms, while the other only found an effect for reduced bleeding.[9][10] MPFF is thought to work by reducing vein inflammation and increasing vein tone (the tightness of the vein).[9] While these products are commonly used in other parts of the world, they are not currently approved by the U.S. Food and Drug Administration for hemorrhoid treatment.[6]

    How could diet affect hemorrhoids?

    A high-fiber diet (25 to 35 grams daily), including adequate fluid intake, is considered to be the best first-line intervention for the management and prevention of hemorrhoids.[11][6] Fiber is found in plant-based foods like vegetables, fruits, whole grains, legumes, nuts, and seeds. Sometimes, going from a low-fiber diet to a high-fiber diet can cause symptoms like bloating, gas, and abdominal discomfort, but slowly increasing fiber intake over time can help to minimize these symptoms. Observational research has suggested that higher consumption of spicy foods is associated with an increased risk of hemorrhoids, but this claim has not been supported by interventional trials.[12][13][7]

    Are there any other treatments for hemorrhoids?

    Sitz baths, which involve sitting in a warm tub of water for 10 to 15 minutes several times a day, are often recommended by healthcare providers for hemorrhoids, but a meta-analysis was unable to find any strong evidence for improvements in pain or healing time. Regardless, people using a sitz bath often reported finding it soothing, and there is no apparent harm from the practice.[14]

    Pelvic floor physiotherapy may play a role in improving long-term outcomes for recurrent hemorrhoids for people with dyssynergic defecation, which is a pelvic floor dysfunction that can make bowel movements difficult. However, most of the research in this field has been related to anal fissures rather than hemorrhoids.[8]

    What causes hemorrhoids?

    Although hemorrhoids are not fully understood, they are thought to occur when the connective tissues within the anal cushion weaken, allowing the blood vessels in the region to become enlarged and displaced.

    Generally, hemorrhoids are associated with conditions that increase pressure in the abdomen or create a shear force against the anal cushions, such as:[6][8][3][11]

    • Constipation (either from hard or lumpy stool or straining during bowel movements)
    • Pregnancy and vaginal delivery
    • Chronic diarrhea
    • Cirrhosis with ascites (fluid in the abdominal cavity)
    • Obesity
    • Anal intercourse
    • Pelvic floor dysfunction
    Why are hemorrhoids more common during pregnancy and postpartum?

    Hemorrhoids are particularly common during the last trimester of pregnancy and the first month postpartum.[15] This increased risk arises for a number of reasons. During pregnancy, the combination of increased blood volume (more circulating blood) and a rise in abdominal pressure from the growing fetus can cause blood to pool in the rectal/anal region.[11] Additionally, progesterone, a hormone that is elevated during pregnancy, relaxes smooth muscles in the walls of veins and the gastrointestinal tract. Veins may become more relaxed, allowing vessels to dilate and blood to pool, while gut motility slows, which can contribute to constipation. Reduced physical activity and changes in diet may also contribute to constipation during pregnancy.[16][11]

    During labor, vaginal delivery creates an immense amount of pressure in the abdomen and rectal area, which can lead to, or worsen, hemorrhoids. Factors that may increase the risk of hemorrhoids during pregnancy and postpartum include a history of constipation or anal problems, straining for more than 20 minutes during delivery, and a newborn birth weight of more than 3,800 grams (8 lbs, 6 oz).[15] Consuming a high-fiber diet with adequate fluids and staying active may help to prevent hemorrhoids in pregnancy and postpartum. A randomized controlled trial found that dietary and behavioral modifications reduced the risk of hemorrhoids by 60%. The dietary component included daily consumption of at least 1.5 liters of fluids, bran (1 tablespoon), 2 to 5 prunes, a serving of nuts, and several servings of fruits and vegetables. Additionally, participants were encouraged to exercise and walk 30–60 minutes per day, 3–5 times per week, and follow good bowel habits (not ignoring the urge to defecate and spending less than 3 minutes on the toilet).[16]

    Update History

    References

    1. ^Alonso-Coello P, Guyatt G, Heels-Ansdell D, Johanson JF, Lopez-Yarto M, Mills E, Zhou QLaxatives for the treatment of hemorrhoids.Cochrane Database Syst Rev.(2005-Oct-19)
    2. ^Johanson JF, Sonnenberg AThe prevalence of hemorrhoids and chronic constipation. An epidemiologic study.Gastroenterology.(1990-Feb)
    3. ^Riss S, Weiser FA, Schwameis K, Riss T, Mittlböck M, Steiner G, Stift AThe prevalence of hemorrhoids in adults.Int J Colorectal Dis.(2012-Feb)
    4. ^Gavriilidis P, Askari A, Gavriilidis E, Di Saverio S, Davies RJ, de'Angelis NEvaluation of the current guidelines for the management of haemorrhoidal disease using the Appraisal of Guidelines Research and Evaluation II instrument.Ann Transl Med.(2023-Mar-31)
    5. ^Emile SH, Elfeki H, Sakr A, Shalaby MTransanal hemorrhoidal dearterialization (THD) versus stapled hemorrhoidopexy (SH) in treatment of internal hemorrhoids: a systematic review and meta-analysis of randomized clinical trials.Int J Colorectal Dis.(2019-Jan)
    6. ^Mott T, Latimer K, Edwards CHemorrhoids: Diagnosis and Treatment Options.Am Fam Physician.(2018-Feb-01)
    7. ^Lohsiriwat VHemorrhoids: from basic pathophysiology to clinical management.World J Gastroenterol.(2012-May-07)
    8. ^Kalkdijk J, Broens P, Ten Broek R, van der Heijden J, Trzpis M, Pierie JP, Klarenbeek BFunctional constipation in patients with hemorrhoids: a systematic review and meta-analysis.Eur J Gastroenterol Hepatol.(2022-Aug-01)
    9. ^Sheikh P, Lohsiriwat V, Shelygin YMicronized Purified Flavonoid Fraction in Hemorrhoid Disease: A Systematic Review and Meta-Analysis.Adv Ther.(2020-Jun)
    10. ^Aziz Z, Huin WK, Badrul Hisham MD, Tang WL, Yaacob SEfficacy and tolerability of micronized purified flavonoid fractions (MPFF) for haemorrhoids: A systematic review and meta-analysis.Complement Ther Med.(2018-Aug)
    11. ^Stefania De Marco, Domenico TisoLifestyle and Risk Factors in Hemorrhoidal DiseaseFront Surg.(2021 Aug 18)
    12. ^Asma Labidi, Feriel Maamouri, Feriel Letaief-Ksontini, Houcine Maghrebi, Meriem Serghini, Jalel BoubakerDietary habits associated with internal hemorrhoidal disease: a case-control studyTunis Med.(2019 Apr)
    13. ^Altomare DF, Rinaldi M, La Torre F, Scardigno D, Roveran A, Canuti S, Morea G, Spazzafumo LRed hot chili pepper and hemorrhoids: the explosion of a myth: results of a prospective, randomized, placebo-controlled, crossover trial.Dis Colon Rectum.(2006-Jul)
    14. ^Lang DS, Tho PC, Ang ENEffectiveness of the Sitz bath in managing adult patients with anorectal disorders.Jpn J Nurs Sci.(2011-Dec)
    15. ^Poskus T, Buzinskienė D, Drasutiene G, Samalavicius NE, Barkus A, Barisauskiene A, Tutkuviene J, Sakalauskaite I, Drasutis J, Jasulaitis A, Jakaitiene AHaemorrhoids and anal fissures during pregnancy and after childbirth: a prospective cohort study.BJOG.(2014-Dec)
    16. ^Poskus T, Sabonyte-Balsaitiene Z, Jakubauskiene L, Jakubauskas M, Stundiene I, Barkauskaite G, Smigelskaite M, Jasiunas E, Ramasauskaite D, Strupas K, Drasutiene GPreventing hemorrhoids during pregnancy: a multicenter, randomized clinical trial.BMC Pregnancy Childbirth.(2022-Apr-30)

    Examine Database References

    1. Hemorrhoids Symptoms - Pirard J, Gillet P, Guffens JM, Defrance PDouble blind study of reparil in proctologyRev Med Liege.(1976 May 15)
    2. Hemorrhoids Symptoms - Panpimanmas S, Sithipongsri S, Sukdanon C, Manmee CExperimental comparative study of the efficacy and side effects of Cissus quadrangularis L. (Vitaceae) to Daflon (Servier) and placebo in the treatment of acute hemorrhoidsJ Med Assoc Thai.(2010 Dec)