How does potassium lower blood pressure?

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    Last Updated: October 25, 2023

    Potassium is well known to reduce blood pressure by inducing diuresis (increased production of urine). However, precisely how potassium achieves this effect is less well-known. Potassium works to lower blood pressure primarily in a specific part of the kidney, known as the distal convoluted tubule.[1] This area of the kidney acts as a potassium sensor. When potassium is low, the kidney holds onto more potassium and water and increases blood pressure. When potassium is high, it allows more potassium and more water to pass by, reducing blood pressure. Furthermore, high sodium intake can increase potassium excretion,[2] indicating that high sodium intakes can exacerbate potassium balance issues in those who consume low potassium diets.

    References

    1. ^Terker AS, Zhang C, McCormick JA, Lazelle RA, Zhang C, Meermeier NP, Siler DA, Park HJ, Fu Y, Cohen DM, Weinstein AM, Wang WH, Yang CL, Ellison DHPotassium modulates electrolyte balance and blood pressure through effects on distal cell voltage and chlorideCell Metab.(2015 Jan 6)
    2. ^Peterson LN, Wright FSEffect of sodium intake on renal potassium excretionAm J Physiol.(1977 Sep)