What are some risk factors for hyperemesis gravidarum?

    Last Updated: October 25, 2023

    Unfortunately, a history of hyperemesis gravidarum in previous pregnancies is a significant risk factor for experiencing it in subsequent pregnancies. In studies that attempt to quantify the risk, the recurrence rate is as low as 15% and as high as 81%, partly related to the variety of definitions studies use for hyperemesis gravidarum.[1] Infection with Heliobacter pylori might increase the risk or severity of hyperemesis gravidarum during pregnancy, and treatment of a confirmed infection is recommended.[2] Other factors that may increase the risk of hyperemesis gravidarum include carrying a female fetus, family history of hyperemesis gravidarum, carrying more than one fetus, black or Asian ethnicity, type I diabetes, and younger age.[3]

    References

    1. ^Dean CR, Bruin CM, O'Hara ME, Roseboom TJ, Leeflang MM, Spijker R, Painter RCThe chance of recurrence of hyperemesis gravidarum: A systematic review.Eur J Obstet Gynecol Reprod Biol X.(2020-Jan)
    2. ^Ng QX, Venkatanarayanan N, De Deyn MLZQ, Ho CYX, Mo Y, Yeo WSA meta-analysis of the association between Helicobacter pylori (H. pylori) infection and hyperemesis gravidarum.Helicobacter.(2018-Feb)
    3. ^Austin K, Wilson K, Saha SHyperemesis Gravidarum.Nutr Clin Pract.(2019-Apr)