Extracts of the plant known as chaste tree (Vitex agnus-castus) have been studied as a possible remedy for hyperprolactinemia. This extract seems to improve premenstrual mastodynia (breast pain) and reduces prolactin levels during the premenstrual phase.[1] A small study done in 2020 found that Vitex agnus-castus was as effective as bromocriptine for reducing prolactin levels.[2] The use of chaste tree as a treatment for mild hyperprolactinemia has been supported by a 2023 review,[3] but more controlled studies are needed to verify these findings.
Mucuna pruriens is another herbal remedy that is sometimes recommended for treating hyperprolactinemia and infertility in men. It has been shown to decrease prolactin levels while also increasing testosterone levels. The prolactin-lowering property is likely because of the increase of dopamine and L-dopa, both of which work to inhibit prolactin release from the pituitary gland.[4][5][6]