Have any supplements been studied for intestinal candidiasis?

    Researchedby:
    Gabrielle Fundaro

    Fact-checked

    by:

    Kamal Patel, Nick Milazzo
    Last Updated: April 24, 2024

    Although probiotics aren’t likely to prevent invasive fungal infections, it appears that they can reduce the risk of Candida colonization in premature babies and critically ill children.[1][2]

    Vitamin D supplementation may be effective for reducing the prevalence of Candida colonization as well as systemic Candida infection (as measured by blood and urine levels of Candida).

    Some studies have also investigated medium-chain triglycerides (MCT) with and without vitamin D. These results are promising, but preliminary.[3][4]

    Certain compounds extracted from oregano, pine, cinnamon, and coffee suppress Candida growth in cell culture models and denture stomatitis (mild oral inflammation due to thrush), but these haven't been studied in the human GI tract.[5][6][7]

    References

    1. ^Hua-Jian Hu, Guo-Qiang Zhang, Qiao Zhang, Shristi Shakya, Zhong-Yue LiProbiotics Prevent Candida Colonization and Invasive Fungal Sepsis in Preterm Neonates: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsPediatr Neonatol.(2017 Apr)
    2. ^Suresh Kumar, Arun Bansal, Arunloke Chakrabarti, Sunit SinghiEvaluation of efficacy of probiotics in prevention of candida colonization in a PICU-a randomized controlled trialCrit Care Med.(2013 Feb)
    3. ^Amanda B Arsenault, Kearney T W Gunsalus, Sonia S Laforce-Nesbitt, Lynn Przystac, Erik J DeAngelis, Michaela E Hurley, Ethan S Vorel, Richard Tucker, Nirupa R Matthan, Alice H Lichtenstein, Carol A Kumamoto, Joseph M BlissDietary Supplementation With Medium-Chain Triglycerides Reduces Candida Gastrointestinal Colonization in Preterm InfantsPediatr Infect Dis J.(2019 Feb)
    4. ^J Xie, L Zhu, T Zhu, Y Jian, Y Ding, M Zhou, X FengVitamin D-supplemented yogurt drink reduces Candida infections in a paediatric intensive care unit: a randomised, placebo-controlled clinical trialJ Hum Nutr Diet.(2019 Aug)
    5. ^Narcisa Mandras, Janira Roana, Daniela Scalas, Simonetta Del Re, Lorenza Cavallo, Valeria Ghisetti, Vivian TullioThe Inhibition of Non- albicans Candida Species and Uncommon Yeast Pathogens by Selected Essential Oils and Their Major CompoundsMolecules.(2021 Aug 15)
    6. ^Ibrahim Alfarrayeh, Edit Pollák, Árpád Czéh, András Vida, Sourav Das, Gábor PappAntifungal and Anti-Biofilm Effects of Caffeic Acid Phenethyl Ester on Different Candida SpeciesAntibiotics (Basel).(2021 Nov 7)
    7. ^Maria Rejane Cruz de Araújo, Panmella Pereira Maciel, Lúcio Roberto Cançado Castellano, Paulo Rogério Ferreti Bonan, Danielle da Nóbrega Alves, Ana Cláudia Dantas de Medeiros, Ricardo Dias de CastroEfficacy of essential oil of cinnamon for the treatment of oral candidiasis: A randomized trialSpec Care Dentist.(2021 May)