What causes intestinal candidiasis?

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    Last Updated: October 25, 2023

    Most cases of IC (and subsequent invasive infection) are seen in preterm infants and critically ill or immunocompromised individuals. Additionally, certain medications, such as antibiotics and steroids, permeable intestines, invasive surgical procedures, hospitalization, and the use of broad-spectrum antibiotics make premature infants more prone to IC and invasive infections.[1]

    People with diabetes may also be more prone to IC, but these findings are complicated by this population’s comparatively high use of antifungals, antibiotics, and steroids (to control inflammation). Intestinal Candida counts can also be elevated as a result of swallowing oral Candida, and oral candidiasis (overgrowth of yeast in the mouth and throat) can occur in people who wear dentures or take the aforementioned medications.[2][3][4]

    References

    1. ^Hua-Jian Hu, Guo-Qiang Zhang, Qiao Zhang, Shristi Shakya, Zhong-Yue LiProbiotics Prevent Candida Colonization and Invasive Fungal Sepsis in Preterm Neonates: A Systematic Review and Meta-Analysis of Randomized Controlled TrialsPediatr Neonatol.(2017 Apr)
    2. ^Thomas A Auchtung, Tatiana Y Fofanova, Christopher J Stewart, Andrea K Nash, Matthew C Wong, Jonathan R Gesell, Jennifer M Auchtung, Nadim J Ajami, Joseph F PetrosinoInvestigating Colonization of the Healthy Adult Gastrointestinal Tract by FungimSphere.(2018 Mar 28)
    3. ^Anthony P Oyom, Emmanuel Okello, Victoria Acam, Christine Aramo, Bashir Mwambi, John C Okiria, Caesar OyetPrevalence and antifungal susceptibility of gastrointestinal candidiasis among diabetic patients: A cross-sectional studyAfr J Lab Med.(2020 Dec 10)
    4. ^Tomasz Gosiewski, Dominika Salamon, Magdalena Szopa, Agnieszka Sroka, Maciej T Malecki, Malgorzata BulandaQuantitative evaluation of fungi of the genus Candida in the feces of adult patients with type 1 and 2 diabetes - a pilot studyGut Pathog.(2014 Oct 15)