Many of the studies on the effects of supplements on kidney stones have focused on the impact of supplementation on the risk of developing stones. Vitamin C has been studied frequently, since it’s converted to oxalate after ingestion and excreted via the urine, which could potentially promote stone formation by increasing oxalate levels in the urine. A couple of studies found a high vitamin C intake was associated with an increased risk of kidney stone risk in men.[1][2] An additional study found evidence that a high intake of vitamin C from supplements was likely responsible for the increased kidney stone risk in men.[3] Other notable supplements that have been studied for their effect on kidney stones include caffeine,[4] calcium, and vitamin D.[5]
References
- ^Taylor EN, Stampfer MJ, Curhan GCDietary factors and the risk of incident kidney stones in men: new insights after 14 years of follow-up.J Am Soc Nephrol.(2004-Dec)
- ^Thomas LD, Elinder CG, Tiselius HG, Wolk A, Akesson AAscorbic acid supplements and kidney stone incidence among men: a prospective study.JAMA Intern Med.(2013-Mar-11)
- ^Pietro Manuel Ferraro, Gary C Curhan, Giovanni Gambaro, Eric N TaylorTotal, Dietary, and Supplemental Vitamin C Intake and Risk of Incident Kidney StonesAm J Kidney Dis.(2016 Mar)
- ^Jiwen Geng, Yuxuan Qiu, Zhefeng Kang, Yupei Li, Jiameng Li, Ruoxi Liao, Zheng Qin, Qinbo Yang, Baihai SuThe association between caffeine intake and risk of kidney stones: A population-based studyFront Nutr.(2022 Oct 10)
- ^Bargagli M, Ferraro PM, Vittori M, Lombardi G, Gambaro G, Somani BCalcium and Vitamin D Supplementation and Their Association with Kidney Stone Disease: A Narrative Review.Nutrients.(2021-Dec-04)