McArdle Disease

    Researchedby:
    Brady Holmer
    Last Updated: October 13, 2024

    McArdle disease, also known as glycogen storage disease type V, is an inherited condition where individuals cannot break down a complex sugar in the body known as glycogen. This disease interferes with normal muscle function and can lead to fatigue, cramps, and muscle pain.

    examine-databaseExamine Database

    McArdle Disease falls under the Pain category.

    392 participants in 2 trials and 1 meta-analysis

    Examine Database: McArdle Disease

    Examine Database References

    1. Power Output - Vorgerd M, Grehl T, Jager M, Muller K, Freitag G, Patzold T, Bruns N, Fabian K, Tegenthoff M, Mortier W, Luttmann A, Zange J, Malin JPCreatine therapy in myophosphorylase deficiency (McArdle disease): a placebo-controlled crossover trialArch Neurol.(2000 Jul)
    2. Power Output - Kley RA, Tarnopolsky MA, Vorgerd MCreatine for treating muscle disorders.Cochrane Database Syst Rev.(2013-Jun-05)
    3. Exercise Tolerance - Vorgerd M, Zange J, Kley R, Grehl T, Hüsing A, Jäger M, Müller K, Schröder R, Mortier W, Fabian K, Malin JP, Luttmann AEffect of high-dose creatine therapy on symptoms of exercise intolerance in McArdle disease: double-blind, placebo-controlled crossover studyArch Neurol.(2002 Jan)