What are the main signs and symptoms of NAFLD?

Most people with NAFLD do not present with symptoms, and the disease remains silent until it has progressed to an advanced stage. In the early stages, fatigue and upper abdominal pain may be reported. Elevated levels of serum alanine aminotransferase and aspartate aminotransferase are also typically observed. In cases of very severe NAFLD, jaundice (i.e., yellowing of the eyes and skin), edema, ascites (i.e., excess fluid trapped in the abdomen), and/or confusion may be present.