How could diet affect NASH?

    Last Updated: October 25, 2023

    Weight loss through a hypocaloric diet and lifestyle changes is recommended to manage other factors that contribute to the disease (e.g., obesity) and to prevent further complications (e.g., cirrhosis). Losing 5% or more of body weight can help reduce liver fat, losing 7% or more of body weight can lead to the resolution of NASH, and losing 10% or more of body weight can stabilize or regress fibrosis. It is also recommended that people with NASH reduce their consumption of saturated fat (particularly from processed red meat), commercially produced fructose, and alcohol consumption.[1]

    Although there are fewer data on other dietary strategies for treating NASH, such as a low-carbohydrate/high-protein diet or intermittent fasting, these dietary strategies may be helpful if people find them easier to follow while still maintaining a caloric deficit.

    Coffee consumption has been associated with a reduced risk of progression to cirrhosis in patients with NASH.[2]