What are some of the main medical treatments for NASH?

    Last Updated: October 25, 2023

    The main approach to managing NASH is weight loss, usually achieved via diet and exercise. Although no standard medications or treatments are approved for NASH, medications are prescribed to manage overall cardiometabolic risk from other comorbid conditions such as diabetes, hyperlipidemia or cardiovascular disease. In severe cases, liver transplantation may be needed if NASH has progressed to end stage liver disease.[1][2]

    Hepatitis A and Hepatitis B vaccinations in unvaccinated individuals would reduce the risk of additional liver damage.

    References

    1. ^Kenneth Cusi, Scott Isaacs, Diana Barb, Rita Basu, Sonia Caprio, W Timothy Garvey, Sangeeta Kashyap, Jeffrey I Mechanick, Marialena Mouzaki, Karl Nadolsky, Mary E Rinella, Miriam B Vos, Zobair YounossiAmerican Association of Clinical Endocrinology Clinical Practice Guideline for the Diagnosis and Management of Nonalcoholic Fatty Liver Disease in Primary Care and Endocrinology Clinical Settings: Co-Sponsored by the American Association for the Study of Liver Diseases (AASLD)Endocr Pract.(2022 May)
    2. ^Westfall E, Jeske R, Bader ARNonalcoholic Fatty Liver Disease: Common Questions and Answers on Diagnosis and Management.Am Fam Physician.(2020-Nov-15)