References
- ^Varacallo M, Seaman TJ, Jandu JS, Pizzutillo POsteopeniaStatPearls.(2022-10)
- ^Karaguzel G, Holick MFDiagnosis and treatment of osteopenia.Rev Endocr Metab Disord.(2010-Dec)
The loss of bone mass with age is a natural process that generally begins after age 30. Bones are in a constant state of remodeling (being built and broken down), and when bone breakdown begins to exceed bone building, gradual reductions in bone density occurs, and over time osteopenia may result.[1] The rate that bone loss leads to osteopenia is highly dependent on genetics, but it is also influenced by modifiable factors beginning in adolescence including physical activity levels, body mass, nutritional status, and the levels of various hormones. Certain disease states, medications, and lifestyle practices may also contribute to an accelerated loss of bone density.[2][1]