Are low levels of any vitamin associated with PPD?

    Last Updated: October 25, 2023

    Many studies have found an association between low circulating (serum) vitamin D and PPD.[1][2][3] In addition, one study has found that lower levels of vitamin B12 six weeks after delivery were associated with higher EPDS scores. Further research is needed to clarify the possible relationship between vitamin B12 and PPD.[4]

    References

    1. ^Amini S, Jafarirad S, Amani RPostpartum depression and vitamin D: A systematic review.Crit Rev Food Sci Nutr.(2019)
    2. ^Quansheng Tan, Shuai Liu, Dajie ChenPoor vitamin D status and the risk of maternal depression: a dose-response meta-analysis of observational studiesPublic Health Nutr.(2021 Jun)
    3. ^Vaziri F, Nasiri S, Tavana Z, Dabbaghmanesh MH, Sharif F, Jafari PA randomized controlled trial of vitamin D supplementation on perinatal depression: in Iranian pregnant mothersBMC Pregnancy Childbirth.(2016 Aug 20)
    4. ^Pooja Dhiman, Raji Ramachandran Pillai, Anand Babu Wilson, Nancy Premkumar, Balaji Bharadwaj, Veena P Ranjan, Soundravally RajendiranCross-sectional association between vitamin B12 status and probable postpartum depression in Indian womenBMC Pregnancy Childbirth.(2021 Feb 17)