The cause of preeclampsia is not fully understood and likely involves both fetal and maternal factors. Abnormal formation of the placenta (which is influenced by genetics, the environment, and the parent’s immune system) may play a central role in preeclampsia development. The placenta in people with preeclampsia often has narrow blood vessels that do not supply enough oxygen and nutrients to the placenta. In response, the parent’s body releases inflammatory cells and chemicals that can affect blood pressure and organs, causing damage.[1][2][3]
References
- ^Ahmed R, Dunford J, Mehran R, Robson S, Kunadian VPre-eclampsia and future cardiovascular risk among women: a review.J Am Coll Cardiol.(2014-May-13)
- ^Roberts JM, Hubel CAThe two stage model of preeclampsia: variations on the theme.Placenta.(2009-Mar)
- ^Wu P, Haththotuwa R, Kwok CS, Babu A, Kotronias RA, Rushton C, Zaman A, Fryer AA, Kadam U, Chew-Graham CA, Mamas MAPreeclampsia and Future Cardiovascular Health: A Systematic Review and Meta-Analysis.Circ Cardiovasc Qual Outcomes.(2017-Feb)