Can certain supplements cause or worsen systemic lupus erythematosus?

    Last Updated: October 25, 2023

    It is possible that supplements aimed at stimulating the immune system could worsen SLE symptoms in some people. For this reason, people with SLE are often advised to avoid supplements like alfalfa, echinacea, and spirulina.[1] There is a case report of a study volunteer developing lupus-like symptoms after ingesting an alfalfa supplement for a hypercholesterolemia study.[2]

    References

    1. ^Bax CE, Chakka S, Concha JSS, Zeidi M, Werth VPThe effects of immunostimulatory herbal supplements on autoimmune skin diseases.J Am Acad Dermatol.(2021-Apr)
    2. ^Akaogi J, Barker T, Kuroda Y, Nacionales DC, Yamasaki Y, Stevens BR, Reeves WH, Satoh MRole of non-protein amino acid L-canavanine in autoimmunity.Autoimmun Rev.(2006-Jul)