What are some of the main medical treatments for traveler’s diarrhea?

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    Last Updated: May 16, 2025

    Treatment for traveler’s diarrhea primarily aims to prevent dehydration and manage symptoms using oral rehydration solutions, loperamide, and bismuth subsalicylate. In severe cases, antibiotics may be prescribed alongside antidiarrheal medications to eliminate the underlying pathogen.

    Treatment of traveler’s diarrhea focuses on preventing dehydration and controlling symptoms (e.g., diarrhea, nausea, abdominal cramping).[1] Oral rehydration solutions that are pre-mixed, or are prepared by adding oral rehydration salts to bottled, boiled, or filtered water, can be used to alleviate dehydration.[2]

    Loperamide — an antimotility and antisecretory medication — can be used to reduce diarrhea, but its use should be avoided in children under 2, and in those with a fever or blood/mucus in the diarrhea.[2][1] Bismuth subsalicylate may also be used to reduce diarrhea, but it tends to have more side effects than loperamide and interacts with several medications.[2][1] In more severe cases of traveler’s diarrhea, antibiotics may be used along with antidiarrheal medications to try to eradicate the pathogen.[2][1]