VVC (commonly referred to as a yeast infection) is a common vaginal fungal infection caused by the overgrowth of Candida species (most often C. albicans). An estimated 70%–75% of women experience one episode of VVC in their lifetime, and 5%–8% of women are affected by recurrent VVC (defined as four or more episodes in one year).
Uncomplicated VVC infections are generally infrequent, mild-to-moderate in severity, occur in women with normal immune function, and resolve with treatment because they're most often caused by the antifungal-sensitive species C. albicans. Complicated VVC, however, is characterized by severe, recurrent episodes that occur in women with diseases that increase their risk of infection and are caused Candida species that are harder to treat.