Intermittent fasting (IF)

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    Last Updated: October 27, 2025

    Intermittent fasting (IF) is a general term for diets that involve prolonged periods of fasting (≥12 hours). Variants of IF include time-restricted eating, alternate-day fasting, and the 5:2 diet. In contrast to intermittent dieting, IF does not necessarily involve intentional caloric restriction; its main focus is on the timing of meals.

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    Examine Database References

    1. Liver Enzymes - Ranjbar M, Shab-Bidar S, Mohammadi H, Djafarian KEffect of Intermittent Fasting on Liver Function Tests: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.Nutr Rev.(2024 Jun 25)
    2. Body Fat - Xie Y, Zhou K, Shang Z, Bao D, Zhou JThe Effects of Time-Restricted Eating on Fat Loss in Adults with Overweight and Obese Depend upon the Eating Window and Intervention Strategies: A Systematic Review and Meta-Analysis.Nutrients.(2024 Oct 5)
    3. Weight - Wang B, Wang C, Li HThe impact of intermittent fasting on body composition and cardiometabolic outcomes in overweight and obese adults: a systematic review and meta-analysis of randomized controlled trials.Nutr J.(2025 Jul 30)
    4. Liver Enzymes - Tavakoli A, Akhgarjand C, Ansar H, Houjaghani H, Khormani A, Djafarian K, Rostamian A, Ranjbar M, Farsani GMThe effects of intermittent fasting on antioxidant and inflammatory markers and liver enzymes in postmenopausal, overweight and obese women with rheumatoid arthritis: a randomized controlled trial.Sci Rep.(2025 Jan 18)
    5. HbA1c - Liu F, Zhang Z, Sun W, Li TThe metabolic effects of intermittent fasting in patients with type 2 diabetes exist in the short term but disappear after its discontinuation: A systematic review and meta-analysis of randomized controlled trials.Nutr Res.(2025 Jun)
    6. HbA1c - Nam T, Oh H, Kim A, Oh YTime-Restricted Eating Improves Glycemic Control in Patients with Type 2 Diabetes: A Meta-Analysis and Systematic Review.Int J Mol Sci.(2025 Jul 29)
    7. Body Fat - Dai ZH, Wan KW, Wong PS, Huang WY, Yu AP, Wong SHAdditional Effect of Exercise to Intermittent Fasting on Body Composition and Cardiometabolic Health in Adults With Overweight/obesity: A Systematic Review and Meta-analysis.Curr Obes Rep.(2025 Jun 19)