Allergen avoidance and medications for accidental exposure are the mainstays of tree nut allergy management. Other treatments, such as immunotherapy and monoclonal anti-IgE antibodies, are under investigation for their efficacy in treating food allergies, including tree nut allergy. The main goal of these immune-modulating therapies is to allow a person with a food allergy to be exposed to their allergen without experiencing a severe reaction.[1][2]