Results to date have been mixed. In one study involving older athletes concurrently taking statin drugs (cholesterol-lowering drugs), supplementation with 200 mg of CoQ10 for 6 weeks improved leg strength, as assessed by leg extensions.[1] On the other hand, another study including younger trained and untrained individuals found that neither a single dose of CoQ10 (200 mg) before exercise nor 2 weeks of continuous supplementation had any significant effect on muscular force production or muscular fatigue.[2]
Regarding anaerobic cardiovascular exercise performance, the evidence of the benefits of CoQ10 supplementation is not conclusive.[1] However, when untrained individuals supplemented with CoQ10 (300 mg) for one week before a 210-minute cycling test, they reported less fatigue rel