Several small and heterogeneous clinical studies suggest that daily supplementation with 500–1,200 milligrams of calcium for up to 3 menstrual cycles improves PMS symptoms such as bloating, food cravings, and pain when compared to placebo. Also, several observational studies have found that PMS symptoms are associated with lower total calcium levels. It is possible that calcium levels are reduced during menstruation, precipitating PMS symptoms. Estrogen may lower calcium in the blood by inhibiting bone resorption. During the menstrual cycle, estrogen has two peaks: right before the luteinizing hormone surge and during the luteal phase. Theoretically, the peaks in estrogen lower total calcium levels. In some, the lower blood calcium levels can increase parathyroid hormone levels and lower calcium levels in the smooth muscle, which in turn might precipitate PMS symptoms such as cramping and pain.[1]
Do calcium supplements help reduce symptoms of PMS?
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•Last Updated: May 16, 2025
Several clinical studies indicate that daily supplementation with 500 to 1,200 milligrams of calcium for up to 3 menstrual cycles can improve premenstrual syndrome (PMS) symptoms like bloating, food cravings, and pain, compared to a placebo. Additionally, lower total calcium levels have been associated with PMS symptoms, which suggests that reduced calcium during menstruation may contribute to these symptoms.