Some of the longest-standing research on berberine’s health effects concerns its use as an antimicrobial.[1][2] Berberine has mixed results when studied for its properties as an antiviral (HIV, coronaviruses, influenza), antibacterial (H. pylori, V. cholerae, S. aureus), and even as an antifungal. Taking this body of evidence into account, berberine’s best use as an antimicrobial seems to be as an adjunctive or combination therapy.[3][2][4]
Does berberine have antimicrobial effects?
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•Last Updated: May 16, 2025
Berberine has been researched for its antimicrobial effects and has shown mixed results as an antiviral, antibacterial, and antifungal treatment. Its most effective use appears to be as an adjunctive or combination therapy.