Does inositol treat mood disorders?

Imaging studies show that inositol levels in the brain are involved in the pathogenesis of mood disorders, including anxiety and depression.^[1] While studies in rodents have shown beneficial effects of inositol on anxiety,^[1][2][3] the current evidence does not support its use for treating mood disorders in humans.^[1][4][5] However, there are few clinical studies on this topic and further high-quality randomized controlled trials are needed.