Imaging studies show that inositol levels in the brain are involved in the pathogenesis of mood disorders, including anxiety and depression.[1] While studies in rodents have shown beneficial effects of inositol on anxiety,[1][2][3] the current evidence does not support its use for treating mood disorders in humans.[1][4][5] However, there are few clinical studies on this topic and further high-quality randomized controlled trials are needed.
Does inositol treat mood disorders?
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•Last Updated: April 23, 2025
Inositol levels in the brain are associated with mood disorders like anxiety and depression, and although rodent studies suggest that it may have beneficial effects on anxiety, current evidence does not support its use for treating mood disorders in humans.