S-adenosylmethionine is claimed to improve joint pain and function in people with knee or hip osteoarthritis. However, studies in this field are small, and their methodological quality is generally low. Consequently, higher-quality evidence is needed to make clear conclusions.[1][2]
Does S-adenosylmethionine treat osteoarthritis?
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•Last Updated: April 23, 2025
S-Adenosylmethionine is suggested to improve joint pain and function in people with knee or hip osteoarthritis, but the existing studies are small and of low methodological quality. Therefore, more robust evidence is required to draw definitive conclusions.