Have any supplements been studied for ankylosing spondylitis?

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    Last Updated: May 16, 2025

    Some research on supplements for ankylosing spondylitis (AS) has been conducted; high doses of omega-3 fatty acids and nanocurcumin showed potential benefits, whereas high serum vitamin D was correlated with lower AS risk, but causal evidence is lacking. Additionally, calcium may support bone health in people with AS but does not directly affect the condition.

    Although some research has been conducted, there isn’t much conclusive evidence. One small trial found that high doses of omega-3 fatty acids reduced AS disease activity, and another found that nanocurcumin reduced the expression of inflammatory markers in people with AS. High serum Vitamin D is correlated with lower risk and severity of AS, but no causal evidence for this relationship exists. Finally, calcium may support bone health for people with AS and osteoporosis, but it doesn’t seem to directly influence AS itself.