Fish oil and N-Acetyl-Cysteine seem to be particularly helpful for depressive episodes.[1][2] Coenzyme Q10, Folic acid, zinc, and probiotics also show some promise for treating bipolar disorder.[2]
Have any supplements been studied for bipolar disorder?
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•Last Updated: May 16, 2025
Fish oil and N-acetyl-cysteine have been found to be particularly helpful for depressive episodes in bipolar disorder. Additionally, coenzyme Q10, folic acid, zinc, and probiotics show some promise for treatment.