Several RCTs have tested the effect of individual supplements on hair loss, given either orally (including vitamin E and saw palmetto) or applied topically to the scalp (including pumpkin seed oil, melatonin, and procyanidin from apples).[1] A number of studies have also examined the effect of oral supplements containing a mixture of compounds, typically a combination of nutrients (e.g., amino acids and vitamins).
Have any supplements been studied for hair loss?
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•Last Updated: May 16, 2025
Supplements that have been studied for hair loss include oral vitamin E, saw palmetto, or a mixture of compounds (such as amino acids plus vitamins), and topical pumpkin seed oil, melatonin, or procyanidin.