Have any supplements been studied for IBS?

Several supplements have been studied and supported by strong evidence for the relief of certain IBS symptoms. Enteric-coated peppermint oil can reduce abdominal pain, and certain probiotic strains are effective for multi-symptom relief.^[1][2] Polymethylsiloxane polyhydrate — an over-the-counter intestinal adsorbent — may also relieve multiple IBS symptoms.^[3] One study has shown that glutamine supplementation may improve the symptoms of post-infectious IBS.^[4] Prebiotics (carbohydrates used preferentially by beneficial gut microbes) aren’t clearly effective, however, and the benefits of other alternatives like traditional Chinese medicinal herbs or aloe vera need to be confirmed in higher-quality studies.^[5]