Many of the studies on the effects of supplements on kidney stones have focused on the impact of supplementation on the risk of developing stones. Vitamin C has been studied frequently, since it’s converted to oxalate after ingestion and excreted via the urine, which could potentially promote stone formation by increasing oxalate levels in the urine. A couple of studies found a high vitamin C intake was associated with an increased risk of kidney stone risk in men.[1][2] An additional study found evidence that a high intake of vitamin C from supplements was likely responsible for the increased kidney stone risk in men.[3] Other notable supplements that have been studied for their effect on kidney stones include caffeine,[4] calcium, and vitamin D.[5]
Have any supplements been studied for Kidney Stones?
Written by:
Fact-checked
by:
•Last Updated: May 16, 2025
Studies on supplements and kidney stones have primarily examined their effect on the risk of developing stones, and vitamin C is frequently studied due to its conversion to oxalate, which may increase stone formation risk. High vitamin C intake has been associated with an increased risk of kidney stones in men, and other supplements like caffeine, calcium, and vitamin D have also been investigated.