How could diet affect type 2 diabetes?

Long-term excess energy intake leads to the accumulation of fat in the liver and pancreas that causes T2D, and calorie restriction can decrease intra-organ fat and put the disease into remission.^[1] There is some evidence that high intake of added fructose, in particular, raises the risk of T2D.^[2] However, any dietary pattern can be effective for treating and preventing T2D as long as it facilitates an energy deficit and promotes sustained weight loss.^[3]